Adam Mickiewicz University Poznań
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HSA-MIR-200B

Id142
Namehsa-mir-200b
Chromosomechr1 (NC_000001)
PrecStart1167104
PrecEnd1167198
Length95
Strandforward
Is at most 5 Mbp to chromosome endYes
Is at most 5 Mbp to chromosome centromereYes
Protein host geneNo
IntronicNo
ClusteredYes
Probability0.4753943169563718
ChrEnd1
ChrCentr1
DOI
Detected in
In presence of
Expression profile
https://doi.org/10.1371/journal.pone.0013176
Elson-Schwab Ilan, Lorentzen Anna, Marshall Christopher J. (2010). MicroRNA-200 Family Members Differentially Regulate Morphological Plasticity and Mode of Melanoma Cell Invasion. PLoS ONE, 5(10), e13176.
malignant melanomaup
https://doi.org/10.4172/1948-5956.1000371
Licheng Wu Richard, Ali Shadan (2015). Identification of Differentially Expressed Mirnas in Appendiceal Mucinous Cystadenocarcinoma from Mucinous Cystadenoma. Journal of Cancer Science & Therapy, 7(11), .
mucinous cystadenocarcinomaup
https://doi.org/10.1038/nm.2401
Korpal Manav, Ell Brian J, Buffa Francesca M, Ibrahim Toni, Blanco Mario A, Celià-Terrassa Toni, Mercatali Laura, Khan Zia, Goodarzi Hani, Hua Yuling, Wei Yong, Hu Guohong, Garcia Benjamin A, Ragoussis Jiannis, Amadori Dino, Harris Adrian L, Kang Yibin (2011). Direct targeting of Sec23a by miR-200s influences cancer cell secretome and promotes metastatic colonization. Nature Medicine, 17(9), 1101-1108.
breast cancerup
https://doi.org/10.1080/15476286.2015.1017208
Pan Yi, Liang Hongwei, Chen Weixu, Zhang Hongjie, Wang Nan, Wang Feng, Zhang Suyang, Liu Yanqing, Zhao Chihao, Yan Xin, Zhang Junfeng, Zhang Chen-Yu, Gu Hongwei, Zen Ke, Chen Xi (2015). microRNA-200b and microRNA-200c promote colorectal cancer cell proliferation via targeting the reversion-inducing cysteine-rich protein with Kazal motifs. RNA Biology, 12(3), 276-289.
colorectal cancerup
https://doi.org/10.1016/j.biopha.2018.07.042
Zhang Zhen, Xing Tongchao, Chen Yanhui, Xiao Jiangmei (2018). Exosome-mediated miR-200b promotes colorectal cancer proliferation upon TGF-β1 exposure. Biomedicine & Pharmacotherapy, 106(), 1135-1143.
colorectal cancerup
https://doi.org/10.1089/nat.2012.0385
Dai Yinmei, Xia Wei, Song Tao, Su Xueting, Li Jie, Li Shaohua, Chen Ying, Wang Wei, Ding Hongmei, Liu Xuemei, Li Hui, Zhao Qiang, Shao Ningsheng (2013). MicroRNA-200b Is Overexpressed in Endometrial Adenocarcinomas and EnhancesMMP2Activity by DownregulatingTIMP2in Human Endometrial Cancer Cell Line HEC-1A Cells. Nucleic Acid Therapeutics, 23(1), 29-34.
endometrial cancerup
https://doi.org/10.1245/s10434-012-2217-6
Kurashige Junji, Kamohara Hidenobu, Watanabe Masayuki, Hiyoshi Yukiharu, Iwatsuki Masaaki, Tanaka Youhei, Kinoshita Koichi, Saito Seiya, Baba Yoshifumi, Baba Hideo (2012). MicroRNA-200b Regulates Cell Proliferation, Invasion, and Migration by Directly Targeting ZEB2 in Gastric Carcinoma. Annals of Surgical Oncology, 19(S3), 656-664.
gastric cancerup
https://doi.org/10.1002/iub.1412
Guo Lixia, Wang Jingyu, Yang Ping, Lu Qiang, Zhang Ting, Yang Yanan (2015). MicroRNA‐200 promotes lung cancer cell growth through FOG2‐independent AKT activation. IUBMB Life, 67(9), 720-725.
lung cancerup
https://doi.org/10.1371/journal.pone.0013176
Elson-Schwab Ilan, Lorentzen Anna, Marshall Christopher J. (2010). MicroRNA-200 Family Members Differentially Regulate Morphological Plasticity and Mode of Melanoma Cell Invasion. PLoS ONE, 5(10), e13176.
malignant melaFalsemaup
https://doi.org/10.4172/1948-5956.1000371
Licheng Wu Richard, Ali Shadan (2015). Identification of Differentially Expressed Mirnas in Appendiceal Mucinous Cystadenocarcinoma from Mucinous Cystadenoma. Journal of Cancer Science & Therapy, 7(11), .
muciFalseus cystadeFalsecarciFalsemaup