Adam Mickiewicz University Poznań
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HSA-MIR-200A

Id141
Namehsa-mir-200a
Chromosomechr1 (NC_000001)
PrecStart1167863
PrecEnd1167952
Length90
Strandforward
Is at most 5 Mbp to chromosome endYes
Is at most 5 Mbp to chromosome centromereYes
Protein host geneNo
IntronicNo
ClusteredYes
Probability0.4753954103778566
ChrEnd1
ChrCentr1
DOI
Detected in
In presence of
Expression profile
https://doi.org/10.1002/cncr.28002
Chen Zheng, Saad Rama, Jia Peilin, Peng DunFa, Zhu Shoumin, Washington M. Kay, Zhao Zhongming, Xu Zekuan, El‐Rifai Wael (2013). Gastric adenocarcinoma has a unique microRNA signature not present in esophageal adenocarcinoma. Cancer, 119(11), 1985-1993.
esophageal adenocarcinomaup
https://doi.org/10.1371/journal.pone.0013176
Elson-Schwab Ilan, Lorentzen Anna, Marshall Christopher J. (2010). MicroRNA-200 Family Members Differentially Regulate Morphological Plasticity and Mode of Melanoma Cell Invasion. PLoS ONE, 5(10), e13176.
malignant melanomaup
https://doi.org/10.3892/mmr.2015.4738
SHI ZHULIANG, HU ZHIQIANG, CHEN DELU, HUANG JIE, FAN JIE, ZHOU SUBO, WANG XIN, HU JIANDAO, HUANG FEI (2015). MicroRNA-200a mediates nasopharyngeal carcinoma cell proliferation through the activation of nuclear factor-κB. Molecular Medicine Reports, 13(2), 1732-1738.
nasopharyngeal carcinomaup
https://doi.org/10.1007/s12038-013-9351-6
Chen Yaqing, Peng Wei, Lu Yixiang, Chen Jianxin, Zhu York Yuanyuan, Xi Tao (2013). MiR-200a enhances the migrations of A549 and SK-MES-1 cells by regulating the expression of TSPAN1. Journal of Biosciences, 38(3), 523-532.
non-small cell lung cancerup
https://doi.org/10.1158/1078-0432.ccr-12-1959
Yu San-Jian, Hu Jing-Ying, Kuang Xia-Ying, Luo Jian-Min, Hou Yi-Feng, Di Gen-Hong, Wu Jiong, Shen Zhen-Zhou, Song Hou-Yan, Shao Zhi-Ming (2013). MicroRNA-200a Promotes Anoikis Resistance and Metastasis by Targeting YAP1 in Human Breast Cancer. Clinical Cancer Research, 19(6), 1389-1399.
breast cancerup
https://doi.org/10.1038/nm.2401
Korpal Manav, Ell Brian J, Buffa Francesca M, Ibrahim Toni, Blanco Mario A, Celià-Terrassa Toni, Mercatali Laura, Khan Zia, Goodarzi Hani, Hua Yuling, Wei Yong, Hu Guohong, Garcia Benjamin A, Ragoussis Jiannis, Amadori Dino, Harris Adrian L, Kang Yibin (2011). Direct targeting of Sec23a by miR-200s influences cancer cell secretome and promotes metastatic colonization. Nature Medicine, 17(9), 1101-1108.
breast cancerup
https://doi.org/10.1186/s12885-017-3930-0
Yu San-Jian, Yang Liu, Hong Qi, Kuang Xia-Ying, Di Gen-Hong, Shao Zhi-Ming (2018). MicroRNA-200a confers chemoresistance by antagonizing TP53INP1 and YAP1 in human breast cancer. BMC Cancer, 18(1), .
breast cancerup
https://doi.org/10.3892/ijmm.2018.3703
Gao Xiaoxu, Cai Yan, An Ruifang (2018). miR‑215 promotes epithelial to mesenchymal transition and proliferation by regulating LEFTY2 in endometrial cancer. International Journal of Molecular Medicine, (), .
endometrial cancerup
https://doi.org/10.1002/cncr.28002
Chen Zheng, Saad Rama, Jia Peilin, Peng DunFa, Zhu Shoumin, Washington M. Kay, Zhao Zhongming, Xu Zekuan, El‐Rifai Wael (2013). Gastric adenocarcinoma has a unique microRNA signature not present in esophageal adenocarcinoma. Cancer, 119(11), 1985-1993.
esophageal adeFalsecarciFalsemaup
https://doi.org/10.3892/ol.2013.1251
LIU SHANG-GUO, QIN XIU-GUANG, ZHAO BAO-SHENG, QI BO, YAO WEN-JIAN, WANG TIAN-YUN, LI HAN-CHEN, WU XIANG-NAN (2013). Differential expression of miRNAs in esophageal cancer tissue. Oncology Letters, 5(5), 1639-1642.
esophageal cancerup